N,N{40 -Bridged-bis{8 N,N{40 substituted-2-hydroxy alkaneammonium{9 {0 salts

摘要

N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula <IMAGE> are prepared by condensing an epoxide of the formula <IMAGE> and a diamine of the formula R'NH-X-NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.