发明名称 |
Substituted azol-1-ylmethanes |
摘要 |
Azol-1-ylmethanes substituted on the methane carbon atom by (a) phenyl or lower alkyl and (b) by a biphenyl-4-yl, 4-phenoxyphenyl, 4-phenylthiophenyl, 4-phenylsulfinylphenyl or 4-phenylsulfonylphenyl group are antimycotic and antibacterial agents. The compounds, of which (biphenyl-4-yl)phenyl-imidazol-1-ylmethane is a typical example, are prepared from the correspondingly substituted carbinol through treatment with thionyl-bis-azole or from the correspondingly substituted methyl halide with the azole or a derivative thereof.
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申请公布号 |
US4118487(A) |
申请公布日期 |
1978.10.03 |
申请号 |
US19750638274 |
申请日期 |
1975.12.05 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
REGEL, ERIK;DRABER, WILFRIED;BUCHEL, KARL HEINZ;PLEMPEL, MANFRED |
分类号 |
C07D233/54;A61K31/41;A61P31/04;A61P31/10;C07C29/143;C07D231/10;C07D231/12;C07D233/56;C07D233/58;C07D233/60;C07D233/64;C07D249/08;C07D521/00;C08K5/3445;C08K5/3472;(IPC1-7):A61K31/41 |
主分类号 |
C07D233/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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