| 摘要 |
Reaction of 5-fluorocytidine with the Vilsmeier-Haack reagent followed by treatment of the reaction mixture with water or a lower alkanol directly yields the previously unknown hydrohalide salts of 2,2'-anhydro-1- beta -D-arabinofuranosyl-5-fluorocytosine as crystalline solids. These compounds are useful as orally or parenterally active immunorepressive or anti-neoplastic agents and as intermediates in the preparation of other acid addition salts, such as the formate of the base compound. |
