发明名称 BASAL SOLUTION FOR HYPERALIMENTATION
摘要 PURPOSE:To obtain a basal solution for hyperalimentation capable of suppressing digestive tract atrophy of patients under operation of total parenteral nutrition(TPN) by blending a human epidermal growth factor(hEGF) with glucose and various electrolytes. CONSTITUTION:A basal solution for hyperalimentation obtained by mixing and dissolving 1mug-10mg/l, preferably 10mug-5mg/l hEGF and 140-480g/l, preferably 150-440g/l glucose in a suitable diluent, such as distilled water for injection, adding various electrolytes thereto, regulating the concentrations of elements constituting the electrolytes in the aqueous solution within the ranges shown in the table and regulating the pH thereof within the range of 4.0-5.5, preferably 4.7-5.1. The above-mentioned basal solution is further blended with 200-1000ml amino acid pharmaceutical in about 7-12% concentration, further blending, as necessary, various vitaminic agents, fatty emulsions, etc., in use and employed as a solution for hyperalimentation used in TPN. The oral nutriment ingestion by patients under operation of TPN is facilitated by administering the aforementioned basal solution and the recovery period can be remarkably shortened.
申请公布号 JPH02191227(A) 申请公布日期 1990.07.27
申请号 JP19890267288 申请日期 1989.10.13
申请人 OTSUKA PHARMACEUT FACTORY INC 发明人 TAMAE HIRONORI
分类号 A61K38/22;A61P1/00 主分类号 A61K38/22
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