发明名称 WERKWIJZE VOOR HET BEREIDEN VAN 2-ARYL-2-(W-(DI- ISOPROPYLAMINO)ALKYL)W-(AZOBICYCLOALKYL)-ALKANA- MIDEN.
摘要 <p>Novel 2-aryl-2-[ omega -(diisopropylamino)alkyl]- omega -(azabicycloalkyl)alkanamides are described herein. The present compounds are useful as anti-arrhythmic agents. The compounds are prepared by reacting an appropriate disubstituted acetonitrile with an appropriate omega -(azabicycloalkyl)alkyl halide and subsequent hydrolysis of the resulting nitrile with concentrated sulfuric acid.</p>
申请公布号 NL7802680(A) 申请公布日期 1978.09.13
申请号 NL19780002680 申请日期 1978.03.10
申请人 G.D. SEARLE & CO. TE SKOKIE, ILLINOIS, VER. ST. V. AM. 发明人
分类号 C07D295/14;C07D295/145;C07D453/06;C07D471/08;C07D487/04;(IPC1-7):61K31/40;07D227/02;07D471/04;07D487/04 主分类号 C07D295/14
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