| 摘要 |
<p>A method for preparing 6-amino-5-R3-2,4,diaminopyrididine-3-oxides which comprises a O-alkylating an R3-substituted 2-cyano acetamide in the presence of an inert organic solvent, thereby forming an enol ether where R is the alkyl from the alkylating agent, b. reacting said enol ether with cyanamide in an inert solvent, thereby forming a 2-R3-3-(cyanimino)-3-Nr1R2 proplonitrile c. reacting the 2-R3-3-(cyanimino)-3-NR1R2-proplonitrile with a hydroxylamine salt and base, thereby forming the 6-amino-5-R3-substituted-2,4,-diamino-pyrimidine-3-oxide .</p> |
