AN POLYAMID FIXIERTES BIOLOGISCH AKTIVES PROTEIN UND VERFAHREN ZU SEINER HERSTELLUNG

摘要

Biologically active protein compositions comprising protein or a protein substrate bound onto a polyamide of the general formula: in which R and R1, which may be the same or different, are polyamide residues bound onto the amido group, R2 is the residue of a compound which can be condensed with formaldehyde and which contains at least one further reactive group, R3 is the residue of a bi- or poly-functional protein reagent, n is 0 or 1, and P is a biologically active protein; these compositions are obtainable by the reaction of a polyamides with amounts, equimolar to one another, of formaldehyde and of a compound condensable with formaldehyde, in a solvent for polyamides, reacting the product thereby obtained with a bi- or poly-functional protein reagent and coupling the resulting reaction product with the biologically active protein or protein substrate.