发明名称 Ascorbic acid synthesis
摘要 {PG,1 Ascorbic acid is prepared from a 1,4-lactone selected from gulono-1,4-lactone, galactono-1,4-lactone, idono-1,4-lactone and talono-1,4-lactone by a process comprising protection of the hydroxyl groups of the lactone so as to form an intermediate having a free hydroxyl group at either, but not both, the 2- or 3-position, oxidizing this free hydroxyl group to a keto group and hydrolyzing the oxidized intermediate to remove the hydroxyl-protecting groups.
申请公布号 US4111958(A) 申请公布日期 1978.09.05
申请号 US19770803020 申请日期 1977.06.03
申请人 PFIZER INC. 发明人 CRAWFORD, THOMAS C.
分类号 C07D307/33;C07D307/62;C07D407/04;C07D493/04;C07F7/18;C07H7/027;(IPC1-7):C07D307/32;C07D319/04 主分类号 C07D307/33
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