发明名称 |
Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins |
摘要 |
Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins are prepared by the two-stage alkylation of the anion of a lower alkyl sulfonamide, R1SO2NH2, using first a compound of the formula: <IMAGE> and second, a compound of the formula: <IMAGE> The compounds produced have renal vasodilatory activity when administered orally and are therefore useful for treating patients with renal impairment.
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申请公布号 |
US4112236(A) |
申请公布日期 |
1978.09.05 |
申请号 |
US19770783998 |
申请日期 |
1977.04.04 |
申请人 |
MERCK & CO., INC. |
发明人 |
BICKING, JOHN B.;CRAGOE, JR., EDWARD J. |
分类号 |
C07C29/143;C07C45/00;C07C49/80;C07C51/29;C07D309/12;(IPC1-7):C07C143/75;A61K31/21;A61K31/19 |
主分类号 |
C07C29/143 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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