发明名称 ARYLETHYNYL DERIVATIVES
摘要 The present invention relates to ethynyl compounds of formula I-C1 wherein R1, R2, R2′, R3, R3′, R6, U, V and W are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof, which are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
申请公布号 HRP20160617(T1) 申请公布日期 2016.07.01
申请号 HR2016P000617T 申请日期 2016.06.07
申请人 F. Hoffmann-La Roche AG 发明人 Green, Luke;Guba, Wolfgang;Jaeschke, Georg;Jolidon, Synese;Lindemann, Lothar;Ricci, Antonio;Rueher, Daniel;Stadler, Heinz;Vieira, Eric
分类号 C07D401/04;A61K31/506;A61P25/18;C07D401/14;C07D403/04;C07D413/04;C07D413/14;C07D498/04 主分类号 C07D401/04
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