发明名称 |
ARYLETHYNYL DERIVATIVES |
摘要 |
The present invention relates to ethynyl compounds of formula I-C1 wherein R1, R2, R2′, R3, R3′, R6, U, V and W are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof, which are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5). |
申请公布号 |
HRP20160617(T1) |
申请公布日期 |
2016.07.01 |
申请号 |
HR2016P000617T |
申请日期 |
2016.06.07 |
申请人 |
F. Hoffmann-La Roche AG |
发明人 |
Green, Luke;Guba, Wolfgang;Jaeschke, Georg;Jolidon, Synese;Lindemann, Lothar;Ricci, Antonio;Rueher, Daniel;Stadler, Heinz;Vieira, Eric |
分类号 |
C07D401/04;A61K31/506;A61P25/18;C07D401/14;C07D403/04;C07D413/04;C07D413/14;C07D498/04 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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