PROCEDE D'INACTIVITE DES SUSPENSIONS DES VIRUS ET DES BACTERIES

摘要

Microorganism can be rendered inactive without impairing their antigenicity or immunogenicity by treating the microorganism with ethyleneimine. The microorganism is placed in a suspension containing ethyleneimine up to a final concentration or 0.005% or 2% V/V. The temperature of the ethyleneimine-containing suspension is maintained between 0.degree. C and 45.degree. C for between a few hours and two days. The excess ethyleneimine is destroyed.