摘要 |
Uracils substituted in the 1-position by a 4substituted phenyl group which can have further optional substitution in the phenyl ring and which has as the 4substituent an aryl group linked through an oxygen, sulfur, sulfinyl or sulfonyl group are prepared by treatment of an aniline derivative substituted in the 4-position by an aryl group with either an acylisocyanate following by cyclization of the resultant urea or an enamine followed by hydrolysis and decarboxylation. The compounds, of which 1-¢3,5-dlchloro-4-(4'-chloro-phenoxy)-phenyl!-uracil is a typical embodiment, demonstrate anticoccidial activity. |