发明名称 |
BAERER FOR TERAPEUTISK AKTIVE FORBINDELSER, MED REGELMESSIG JEVN, PROTRAHERT LEGEMIDDELVIRKESTOFFAVGIVELSE |
摘要 |
<p>Nontoxic sustained release pharmaceutical compositions containing one or more nonionic, lipophilic drugs in a cured low temperature vulcanizable (LTV) silicone elastomer excipient are prepared substantially free of toxic vulcanizing agents or drug-reactive by-products in the elastomeric material by curing an admixture of the drug or drug containing core, LTV-methylvinylsiloxane units containing linear dimethylpolysiloxane and a dimethylpolysiloxane crosslinking composition containing silicon linked H atoms using a noble metal-based catalyst. The resultant compositions are characterized by good physical properties and a constant rate of drug release in the body over long periods of time.</p> |
申请公布号 |
NO138189(C) |
申请公布日期 |
1978.07.26 |
申请号 |
NO19720004203 |
申请日期 |
1972.11.17 |
申请人 |
SCHERING AKTIENGESELLSCHAFT, BERLIN UND BERGKAMEN, |
发明人 |
SCHOEPFLIN, GISELA,;FUCHS, PETER,;KOLB, KARL HEINZ, |
分类号 |
A61J3/07;A61K9/00;A61K9/02;A61K9/06;A61K9/20;A61K9/22;A61K9/28;A61K9/70;A61K47/34;A61K47/36;C08L83/04;(IPC1-7):61K47/00 |
主分类号 |
A61J3/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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