发明名称 2-Amino oxazolines and process for making the same
摘要 Cyclopropylmethylamines which are substituted on the 2-position of nitrogen heterocycles so as to provide new compounds of the formula <IMAGE> I wherein A is oxygen, sulfur, or nitrogen; the other "R" variables in general are hydrogen, lower-alkyl, cyclopropyl, or lower-alkyl substituted cyclopropyl; and the n's are the numbers 0 to 3, inclusive, and acid addition salts thereof, are disclosed. The compounds are cardiovascular agents, which are depressive of the central nervous system. Their effects include hypnosis, analgesia, and neuro-modulation. They can be used as anti-hypertensive agents.
申请公布号 US4102890(A) 申请公布日期 1978.07.25
申请号 US19760713381 申请日期 1976.08.11
申请人 SCIENCE-UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE 发明人 MALEN, CHARLES;DESNOS, MONIQUE;LAUBIE, MICHEL;POIGNANT, JEAN-CLAUDE
分类号 C07C275/18;C07D233/48;C07D263/28;C07D265/06;C07D277/18;(IPC1-7):C07D263/28 主分类号 C07C275/18
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