摘要 |
Cyclopropylmethylamines which are substituted on the 2-position of nitrogen heterocycles so as to provide new compounds of the formula <IMAGE> I wherein A is oxygen, sulfur, or nitrogen; the other "R" variables in general are hydrogen, lower-alkyl, cyclopropyl, or lower-alkyl substituted cyclopropyl; and the n's are the numbers 0 to 3, inclusive, and acid addition salts thereof, are disclosed. The compounds are cardiovascular agents, which are depressive of the central nervous system. Their effects include hypnosis, analgesia, and neuro-modulation. They can be used as anti-hypertensive agents.
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申请人 |
SCIENCE-UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE |
发明人 |
MALEN, CHARLES;DESNOS, MONIQUE;LAUBIE, MICHEL;POIGNANT, JEAN-CLAUDE |