摘要 |
6(EQ)-R4-1,2,3,4,5,6-Hexahydro-3-R1-11(ax)-R3-11(eq)-CH2Z-2,6-methano- 3-benzazocines, useful as analgesic agents and narcotic antagonists, and 1-R1-2-Q-4a alpha -R3-5 alpha -R4-1,2,3,4,4a,5,10,10a-octahydro-3,5-ethano- (and 3,5-ethano) benzo[g]quinolines, useful as analgesic agents, prepared by heating, with formic acid in an organic solvent or with certain ammonium formates in the absence of a solvent, certain 1,2,3,4,4a,5,10,10a-octahydro-2,5-methanobenzo[g]quinolines, the latter prepared by acid catalyzed cyclization of a 3-benzyl-2-azabicyclo[2.2.2]-oct-5-ene.
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