发明名称 |
Production of serum albumin |
摘要 |
A serum albumin fraction is prepared in high yield and purity from plasma and other albumin-containing blood protein fractions by contacting with a resinous polymeric material having a high capacity for adsorption of albumin, heating at 65 DEG C-72 DEG C for about 1-4 hours while maintaining a pH of 5.0-5.5, and then selectively eluting the albumin from the resin-protein mixture at a pH of 3.5-4.5. The resinous polymeric materials are water-insoluble, cross-linked polyelectrolyte copolymers of ethylene and maleic anhydride containing pendant dimethylaminopropyl functional groups.
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申请公布号 |
US4097473(A) |
申请公布日期 |
1978.06.27 |
申请号 |
US19770828013 |
申请日期 |
1977.08.26 |
申请人 |
MONSANTO COMPANY |
发明人 |
LEWIS, JR., CHARLES;SCHUCK, JAMES M. |
分类号 |
C07K14/76;A61K35/14;A61K35/16;A61K38/16;A61K38/38;C07K14/435;C07K14/765;(IPC1-7):C07G7/00 |
主分类号 |
C07K14/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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