发明名称 |
BETA-LACTAM COMPOUNDS,PREPARATION PROCESS THEREOF AND THEIR USE AS MEDICINES |
摘要 |
<p>The title compounds correspond to the formula I; the symbols used are defined in Claim 1. The compounds are obtained by acylation of the optionally silylated amino group of the antibiotic derivatives of the formula II with a derivative of a carboxylic acid or thiocarboxylic acid of the formula III to form a -CE-NH linkage (E = oxygen or sulphur). Protective groups which are present are subsequently eliminated, and the beta -lactam compounds are finally obtained as free acids or as non-toxic salts. The compounds belong to the penicillin and cephalosporin series and can accordingly be used as antibiotics and as animal feed additives. They have a broad spectrum of action while being well tolerated. <IMAGE></p> |
申请公布号 |
GR60558(B) |
申请公布日期 |
1978.06.22 |
申请号 |
GR19760151062 |
申请日期 |
1976.06.22 |
申请人 |
BAYER AG |
发明人 |
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分类号 |
A61K31/43;A61K31/435;A61K31/505;A61K31/535;A61K31/545;A61K31/546;A61P31/04;C07D233/32;C07D233/38;C07D499/00;C07D499/64;C07D501/20;C07D501/36;C07D501/38 |
主分类号 |
A61K31/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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