Preparation of p-aminobenzotrifluoride

摘要

p-Aminobenzotrifluoride is prepared by aminating p-chlorobenzotrifluoride in an essentially nonaqueous solvent in the presence of a catalyst system comprising a copper compound and a selected salt compound. Exemplary is the reaction of p-chlorobenzotrifluoride with ammonia in the presence of cuprous chloride and potassium fluoride to yield p-aminobenzotrifluoride.