发明名称 |
Inert core implant pellet |
摘要 |
A novel spherical implant pellet containing estradiol, estradiol benzoate, or mixtures thereof as the sole active ingredients which exhibits a substantially constant drug release rate over a timer period and substantially abrupt termination of drug release at the end of the time period is prepared which has an inert spherical core of a diameter of about 2-10 mm and a uniform coating of about 0.05-1 mm completely covering the core, the coating comprising about 5-99% suitable carrier and 1-95% drug. A drug may be administered at a constant rate over a chosen period by implanting the novel pellet and the release is substantially abruptly terminated at the end of said period without removing the pellet.
|
申请公布号 |
US4096239(A) |
申请公布日期 |
1978.06.20 |
申请号 |
US19760735727 |
申请日期 |
1976.10.26 |
申请人 |
SYNTEX CORPORATION |
发明人 |
KATZ, MARTIN;KENT, JOHN S. |
分类号 |
A61K31/555;A61K9/00;A61K9/16;A61K9/22;(IPC1-7):A61K9/22;A61K31/56 |
主分类号 |
A61K31/555 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|