| 摘要 |
Daunorubicin derivatives of the formula: <IMAGE> wherein R1 represents a group of the formula: <IMAGE> in which (i) X1 and X2 both represent oxygen or both represent sulphur and the symbols R3 each represent alkyl of 1 through 4 carbon atoms, phenyl or phenyl substituted in the para-position by methyl, methoxy or methylthio, or together form an alkylene radical of 2 through 4 carbon atoms, or (ii) one of X1 and X2 represents oxygen and the other represents sulphur and the symbols R3 together form an alkylene radical of 2 through 4 carbon atoms, and R4 represents hydrogen, alkyl of 1 through 4 carbon atoms or phenyl, and R2 represents hydrogen or trifluoroacetyl, are new compounds possessing anti-tumour properties. |
