PHENYLACETIC ACID DERIVATIVES

摘要

1511095 Phenylacetic acid derivatives BOEHRINGER MANNHEIM GmbH 1 July 1976 [19 July 1975] 27420/76 Heading C2C The invention comprises phenylacetic acid derivatives of the formula wherein A is an aryl radical optionally substituted one or more times by halogen, CF 3 , alkyl, alkoxy, alkenyloxy, alkoxyalkoxy, mono- or dialkylamino or aryloxy, or a heterocyclyl radical optionally substituted by halogen, alkyl or alkoxy, Y is C 1-3 alkylene, and R 1 and R 2 each are H or C 1-5 alkyl and physiologically compatible salts and esters thereof, and their preparation by known methods. The preparation of intermediates used in the preparation of the above compound is also described. Pharmaceutical compositions, suitable for oral or parenteral administration, contain the above phenylacetic acid derivatives in admixture with solid or liquid diluents or carriers. The compounds possess hypoglycaemic and/or hypolipidaemic activities.