发明名称 |
PROCEDE POUR LA PREPARATION DES 3-FLUORCEPHALOSPORINES |
摘要 |
<p>An ester of a 7-acylamido-3-fluoro-3-cephem-4-carboxylic acid is prepared by reacting a 3-sulfonate ester of an ester of a 7-acylamido-3-hydroxy-3-cephem-4-carboxylic acid in an inert solvent with an inorganic fluoride in the presence of an 18-crown-6 ether and at a temperature of from about -20 DEG C. to about +25 DEG C.</p> |
申请公布号 |
RO63021(A) |
申请公布日期 |
1978.05.15 |
申请号 |
RO19740078105 |
申请日期 |
1974.03.20 |
申请人 |
ELI LILLY AND CO,US |
发明人 |
KOPPEL,GARY A.,US |
分类号 |
A61K31/545;A61K31/546;A61P31/04;C07B61/00;C07D501/00;C07D501/04;C07D501/20;C07D501/59;(IPC1-7):07D501/60 |
主分类号 |
A61K31/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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