| 摘要 |
<p>Process for the manufacture of 1-(N- beta -cyanethylamino)-3-acylaminobenzenes of the formula (1) <IMAGE> (1) in which R1 represents hydrogen, methyl or alkoxy of 1 to 4 carbon atoms, R2 represents hydrogen, alkyl from 1 to 3 carbon atoms or phenyl, R3 represents hydrogen or alkyl from 1 to 3 carbon atoms, and n represents the integer 0 or 1, which comprises reacting 1 mole of an amino of the formula (2) <IMAGE> (2) in which R1, R2 and R3 are defined as above, with 1 to 1.75 moles of acrylonitrile between 70 DEG and 150 DEG C in water with the addition of 1 to 30% by weight of an organic carboxylic acid or carbonic acid, and oxethylating the compound at the said formula (1) obtained, if n stands for the integer 0, without or after isolation, with 1 to 10 moles of ethylene oxide between 50 DEG and 100 DEG C.</p> |
