发明名称 |
PROTEIN FROM YEAST FOR CANCER DIAGNOSIS |
摘要 |
A specific type of protein, which has been designated B-protein (Bucovaz-protein), is present in most serum of individuals with cancer. The B-protein interacts with a low molecular weight protein component, which is released by the coenzyme A-synthesizing protein complex (CoA-SPC) of Bakers' yeast during the course of CoA synthesis. This low molecular weight protein, for purposes of identification, is referred to as binding protein. The binding protein has a molecular weight of 10,000 to 15,000. Interaction of radioactively labeled binding protein of CoA-SPC with the B-protein of serum provides a marker for the detection of cancer. Of 3005 serums assayed, which included 908 patients diagnosed as having cancer, the B-protein assay agreed with the clinical diagnosis in more than 89% of the cases. |
申请公布号 |
AU1920576(A) |
申请公布日期 |
1978.05.11 |
申请号 |
AU19760019205 |
申请日期 |
1976.11.01 |
申请人 |
BUCOVAZ, E.T., MORRISON, J.C., MORRISON ,W.C. AND WHYBREW, W.D. |
发明人 |
EDSEL T. BUCOVAZ;JOHN C. MORRISON;WILLIAM C. MORRISON;WALTER D. WHYBREW |
分类号 |
G01N33/574;A61K36/06;C12N9/00;C12Q1/25;G01N33/60;G01N33/68 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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