发明名称 |
Radioimmunoassay for thyroid-stimulating hormone (TSH) |
摘要 |
This invention provides a method for the radioimmunoassay of thyroid-stimulating hormone which utilizes a rapid and convenient version of a double antibody procedure. Highly purified second antibody is bound, by means of covalent bonds, to hydrolyzed polyacrylamide particles to produce a two-phase system. The solid phase comprises immobilized second antibody bound to the reaction product of labeled and unlabeled thyroid-stimulating hormone with the first antibody (first antibody-antigen complex) and the liquid phase comprises free (unbound) labeled and unlabeled thyroid-stimulating hormone. The two phases are separated and the radioactivity of either phase is measured.
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申请公布号 |
US4088746(A) |
申请公布日期 |
1978.05.09 |
申请号 |
US19760742391 |
申请日期 |
1976.11.11 |
申请人 |
BIO-RAD LABORATORIES, INC. |
发明人 |
BLAKEMORE, JUDITH I.;LEWIN, NATHAN;BURGETT, MICHAEL W. |
分类号 |
G01N33/53;G01N33/78;(IPC1-7):A61K43/00;G01N33/16 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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