发明名称 |
WERKWIJZE VOOR DE BEREIDING VAN NIEUWE 17-SPIRO- SULTINE STEROIDEDERIVATEN EN OVEREENKOMSTIGE GAMMA-HYDROXYZUREN, WERKWIJZE VOOR DE BEREIDING VAN THERAPEUTISCHE PREPARATEN EN GEVORMDE GE- NEESMIDDELEN. |
摘要 |
Novel 17-spirosultines of steroids and the corresponding gamma -hydroxy acids of the formula <IMAGE> I wherein R1 is alkyl of 1 to 4 carbon atoms, A is hydrogen and B is hydrogen or hydroxyl of beta configuration or A and B together form a double bond, X and Y together form the group <IMAGE> or X is -OH and Y is <IMAGE> and M is selected from the group consisting of hydrogen, -NH4 and an alkali metal having a remarkable progestomimetic and antialdosteronic activity and a novel process for their preparation and novel intermediates. |
申请公布号 |
NL7711787(A) |
申请公布日期 |
1978.05.02 |
申请号 |
NL19770011787 |
申请日期 |
1977.10.27 |
申请人 |
ROUSSEL-UCLAF, S.A. TE PARIJS. |
发明人 |
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分类号 |
A61K31/565;A61K31/58;A61P5/38;C07J21/00;C07J31/00;C07J33/00;(IPC1-7):07J33/00;07J1/00;61K31/565;61K31/58 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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