发明名称 PROCESS FOR THE PREPARATION OF 3,4-DIHYDRO-2-METHYL-4-OXO-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC ACID-1,1-DIOXIDE AND ITS USE AS AN INTERMEDIATE
摘要 Process for production of 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide by hydrolysis, in the presence of hydroxide ions, of an alkyl or aralkyl ester thereof followed by precipitation of the acid at pH below 6.0 and its use as an intermediate for the production of N-(2-pyridyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carbox amide-1,1-dioxide and the analogous N-(2-thiazolyl)-compound, effective antiinflammatory agents.
申请公布号 ZA7703248(B) 申请公布日期 1978.04.26
申请号 ZA19770003248 申请日期 1977.05.30
申请人 PFIZER INC 发明人 HAMMEN P
分类号 C07D279/02 主分类号 C07D279/02
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