| 摘要 |
1530975 9,11 - Dihalo - 16 - methyl steroids ROUSSEL UCLAF 2 March 1977 [2 March 1976] 08713/77 Heading C2U The invention comprises compounds of formula (wherein L is H or C 1-18 acyl, and either X is Cl or Br and Y is Cl, or X is Cl and Y is F); and their preparation from the corresponding 9(11)- enes by halogenation, e.g. with an N-X-succinimide or -acetamide in conjunction with HY or LiY, optionally followed by acylation/deacylation interconversions at C-21. Topical anti-inflammatory compositions comprise a compound I and a carrier. |
