| 摘要 |
1299421 Pyridazine derivatives SANDOZ Ltd 12 Jan 1970 [21 Jan 1969] 1363/70 Heading C2C The invention comprises compounds of formula wherein X is (a) NHNH 2 (and acid addition salts) or (b) Cl or Br, and R 1 , R 2 are each C 3-5 alkenyl of which no doubly-bonded carbon atom is N-attached, or R 1 is H. (a) are prepared by reacting (b) with hydrozine, while (b) are prepared by reacting 3,6-dichloro- or dibromopyridazine with R 1 R 2 NH. Therapeutic compositions for oral or parenteral administration comprise the above compounds (a), which have hypotensive/antihypertensive and anoreciant activity.
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