| 摘要 |
3 alpha -Hydroxy-5 alpha ,ss-pregnan- and -19-norpregnan-20-ones which have in position 21 a substituent selected from cyano, azido and cycloamino and which can additionally be substituted in position 11 by another oxo group and can have in positions 2 alpha , 2ss, 3ss and 16 other substituents defined in Claims 1, 5 and 8, and which can additionally contain a double bond in the 1,2 and/or 4,5 position, have anaesthetic effects and provide short induction times. They are prepared by reacting a corresponding steroid which has in position 21 an easily eliminated radical with a compound which supplies cyanide or azide ions or with an appropriate cyclic amine. |
