发明名称 Reactive, stable metal and organic cpd. compsns. - comprising metal surface coated with polymer and coupled to enzymes, protein(s) etc.
摘要 <p>Water-insol. compsn. comprises an organic cpd., (I) having biological or chemical activity bound to a metal substrate (II). The (II) has its surface coated with a polymer (III) formed by condsn. of an aminobenzoic acid with an aldehyde, to which the (I) is bound. (I) include water repellents, enzymes, antibiotics, antibodies, biopolymers such as proteins, polysaccharides and peptides. The compsns. can be repeatedly used. The (I) is more heat stable and resistant to inactivation. The high density compsn. is easily removed from a liq. medium; When (II) is magnetic, precise control of the use of the compsn. is effected by use of magnetic fields, the compsns. may be used in purificn. extn., sepn. etc., of (I), or mixts of (I) esp. when (I) are enzymes and antisera. When antisera are bound to metal bars, the prods., may be used in simplified radio immunoassays. The compsns. may be used in bio-engineering, esp. when (II) is Ni or Al, so that the prods. can easily be machined, formed into wires, sheets etc.</p>
申请公布号 DE2644249(A1) 申请公布日期 1978.04.06
申请号 DE19762644249 申请日期 1976.09.30
申请人 ABBOTT LABORATORIES 发明人 FREDERICK KENNEDY,JOHN;FRANK CHAPLIN,MARTIN
分类号 C12N11/14;G01N33/543;G01N33/553;(IPC1-7):C07G7/00;C07G7/02;G01N33/16;B05D5/00;B05D7/14 主分类号 C12N11/14
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