PROCEDIMIENTO PARA METILIZAR CEFALINA Y SERINCEFALINA.

摘要

Phosphatidylethanolamine or serine, which may be pure or be present in the mixture with other phosphatides, can be methylated in a simple and gentle manner by reacting the phosphatides with formaldehyde in the presence of formic acid. In which connection at least 2 moles formaldehyde and 2 moles formic acid are employed per amino group, whereafter the so-obtained dimethylcephalin or dimethylserinecephalin may optionally be methylated further with methyl iodide to the corresponding quaternary ammonium compounds.