| 摘要 |
<p>1400985 Polymers containing iodine PHARMACIA AB 19 Sept 1973 [19 Sept 1972] 43942/73 Heading C3R A polymer for use as an X-ray contrast material contains iodine-substituted aromatic groups bound in or to the polymer by covalent bonds and also contains hydrophilic groups, the polymer being in the form of a three-dimensional network held together by covalent bonds and being insoluble in water but which swells in water to form a gel containing from 10 to 99% by weight of water. The polymers are obtained by reacting one or more at least monofunctional iodine-substituted aromatic compounds having X-ray contrast properties and one or more at least bifunctional cross-linking agents with each other in one or more steps, at least one of the reactants containing or giving rise to at least one hydrophilic group. The iodinesubstituted aromatic group may be a triiodobenzene group and the hydrophilic group may be a carboxyl, hydroxyl or amino group. In examples polymers are obtained by reacting 5 - acetylamino - 2,4,6 - triiodo - N - methylisophthalic acid monoamide with 1,4- butanedioldiglycide ether, by reacting 3 - acetylamino - 5 - acetylamino - 2,4,6 - triiodobenzoic acid with 1,4-butanedioldiglycide ether, by reacting 3-acetylamino-5-acetylmethylamino-2,4,6-triiodobenzoic acid with 1,4-butanediol-diglycide ether and by reacting 3-acetylamino-2,4,6-triiodobenzoic acid with 1,4-butanedioldiglycide ether.</p> |
