发明名称 METHOD OF SYNTHESIZING 1-(TETRAHYDRO-2-FURANYL)-5-FLUOROURACIL
摘要 <p>1503614 Process for preparing 1-(tetrahydro- 2-furanyl)-5-fluorouracil UNIVERSITY OF UTAH 14 April 1975 [6 May 1974] 15282/75 Heading C2C [Also in Division C3] A novel process for preparing 1-(tetrahydro-2- furanyl)-5-fluorouracil comprises reacting bistrimethylsilyl-5-fluorouracil with 2-halotetrahydrofuran, and, if necessary, removing the trimethyl silyl protecting group. 1 - (Tetrahydro - 2 - furanyl) - 5 - fluorouracil is an antimetabolite active against cancer of the breast and of the gastro-intestinal tract.</p>
申请公布号 GB1503614(A) 申请公布日期 1978.03.15
申请号 GB19750015282 申请日期 1975.04.14
申请人 UNIVERSITY OF UTAH 发明人
分类号 C07D405/04;(IPC1-7):07D405/04;61K31/505 主分类号 C07D405/04
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