| 发明名称 |
Process using alkali fusion for decyanation of tert.-nitriles |
| 摘要 |
An improvement in the decyanation of tertiary nitriles comprises the alkali fusion of the nitriles. Exemplary are the preparation of chlorpheniramine and brompheniramine by heating the respective nitriles in liquid sodium or potassium hydroxide at from 100 DEG -200 DEG .
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| 申请公布号 |
US4079061(A) |
申请公布日期 |
1978.03.14 |
| 申请号 |
US19760698448 |
申请日期 |
1976.06.21 |
| 申请人 |
SMITHKLINE CORPORATION |
发明人 |
BERKOFF, CHARLES E.;RIVARD, DONALD E. |
| 分类号 |
C07D213/38;C07D213/55;(IPC1-7):C07D211/82 |
主分类号 |
C07D213/38 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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