发明名称 |
SUBSTITUTED L-ARGININAMIDES AND THEIR SALTS |
摘要 |
<p>The arginamides correspond to the formula: <IMAGE> in which Ar represents various aromatic groups and R represents one of the following groups: <IMAGE> The detailed definition of the Ar groups and the symbols in the R groups is found in Claim 1. The compounds and their acid addition salts are prepared from L-arginine by a three-step process. They have a specific inhibitory action against thrombin and can be used, preferably in the form of pharmaceutical preparations, for the treatment and for the prophylaxis of thromboses.</p> |
申请公布号 |
IL53685(D0) |
申请公布日期 |
1978.03.10 |
申请号 |
IL19770053685 |
申请日期 |
1977.12.23 |
申请人 |
OKAMOTO S;MITSUBISHI CHEMICAL IND LTD |
发明人 |
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分类号 |
C07C311/18;A61K38/00;C07C311/19;C07D209/44;C07D211/16;C07D211/32;C07D211/34;C07D223/06;C07D225/02;C07D265/30;C07D295/185;C07D307/14;C07D307/52;C07D309/04;C07D311/14;C07D319/18;C07D319/22;C07D327/08;C07D333/76;C07D405/12;C07K5/072 |
主分类号 |
C07C311/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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