| 摘要 |
A process for the preparation of calcium salts of alpha -ketocarboxylic acids comprising reacting an alpha -ketocarboxylic acid with an amine, to afford a salt, said salt being soluble in the reaction medium, treating said salt with a source of calcium ion to afford the calcium salt of the alpha -ketocarboxylic acid, said salt being substantially insoluble in said reaction medium, and isolating said calcium salt from the reaction medium. This process is especially useful for the preparation of calcium salts of alpha -keto analogues of essential alpha -amino acids.
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