Hypolipaemic 3-aminothiophenes of the formula <IMAGE> in which R1 is lower alkyl, aryl or aralkyl and R2 is lower alkoxy, and salts thereof are prepared starting from the corresponding 3-ketotetrahydrothiophene oximes. The resulting compounds of the formula I can be converted into the corresponding carboxylic acids or N-alkylated or N-aralkylated.
申请公布号
NO772917(A)
申请公布日期
1978.02.24
申请号
NO19770002917
申请日期
1977.08.22
申请人
HOFFMANN-LA ROCHE & CO. AG., F.,
发明人
CONFALONE, PASQUALE NICHOLAS,;PIZZOLATO, GIACOMO,;USKIKIVIC, MILAN RADOJE,;ROUGE, MARIANNE,