发明名称 |
PYRROLO(2,1-B)(3)BENZAZEPINES |
摘要 |
Pyrrolo[2,1-b]-3-benzazepines of the formula <IMAGE> and their salts and cis/trans geometrical isomers are prepared in pure form or as mixture. The substituents are defined in Claim 1. These compounds are obtained by dehydration of corresponding compounds which have a hydroxyl group in position 11. The isomers, preferably the E isomer, can be obtained from the mixture of isomers by chromatographic separation. The resulting compounds can be used as skeletal muscle relaxants or sedatives. |
申请公布号 |
ZA7603990(B) |
申请公布日期 |
1978.02.22 |
申请号 |
ZA19760003990 |
申请日期 |
1976.07.02 |
申请人 |
MERCK & CO INC |
发明人 |
ROKACH J;ROONEY C;ATKINSON J |
分类号 |
A61K31/00;A61K31/55;A61P21/02;A61P25/18;A61P25/20;C07C229/38;C07D207/32;C07D207/327;C07D207/34;C07D217/24;C07D487/04;C07D498/04 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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