发明名称 1-Substituted-4-(2-oxo-hexahydro-1-pyrimidinyl)-piperidine
摘要 Piperidines of the formula <IMAGE> in which R1 stands for optionally substituted aryl, R2 for hydrogen, lower alkyl, lower alkenyl, acyl or alpha -aryl-lower alkyl, R3 for a free or substituted hydroxyl group, alk for lower alkylene which separates the two nitrogen atoms by 2 or 3 carbon atoms, R4 represents hydrogen or lower alkyl and n represents an integer from 1 to 4, and their salts as well as processes for their manufacture and pharmaceutical compositions comprising such compounds, and a process for lowering the blood pressure wherein such compositions are administered to a warm-blooded host.
申请公布号 US4075208(A) 申请公布日期 1978.02.21
申请号 US19760652965 申请日期 1976.01.28
申请人 CIBA-GEIGY CORPORATION 发明人 WILHELM, MAX;EICHENBERGER, KURT;SCHROTER, HERBERT;OSTERMAYER, FRANZ
分类号 A61K31/445;A61K31/495;A61K31/635;C07D213/75;(IPC1-7):A61K31/50;C07D401/04 主分类号 A61K31/445
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