| 摘要 |
1397193 Thienopyrimidines SUMITOMO CHEMICAL CO Ltd 27 Feb 1973 [28 Feb 1972] 9576/73 Heading C2C Novel compounds (I) wherein R 1 , R 2 and R 3 are independently a hydrogen atom, an alkyl group, an alkoxy group, a nitro group, a trifluoromethyl group, an alkylthio group, an alkylsulfonyl group or a halogen atom; and R is a hydrogen atom, an alkyl group, an alkenyl group, an aralkyl group, an alkoxylalkyl group, a cycloalkylalkyl group, a haloalkyl group, an alkylthioalkyl group, an alkoxycarbonylalkyl group, an alkanoyloxyalkyl group, or a group of the formula (wherein n is an integer of 1 to 3; and R 4 and R 5 are alkyl groups, or R 4 and R 5 may form together with the adjacent nitrogen atom an unsubstituted or optionally substituted 5- or 6- membered heterocyclic ring, which may contain a further hetero atom) are made by cyclizing (II) in the presence of ammonia. Pharmaceutical preparations showing antiinflammatory, analgesic, antiviral, uricosuric, diuretic and CNS activities contain (I) as active ingredient. Administration may be orally or parenterally. |
