Platelet aggregation inhibiting carbostyrils, their compositions and method of use

摘要

Novel benzcycloamide derivatives represented by the general formula, (I) wherein R1 is hydrogen, C1-4 alkyl, C2-4 alkenyl or aralkyl; B is -CH2-, -CH2-CH2- or -CH=CH-; A is (wherein R2 and R3 may be the same or different and are respectively hydrogen or C1-4 alkyl) or -CH=CH-; R4 is -OR5 (wherein R5 is hydrogen, C1-8 alkyl, cycloalkyl or aralkyl) or (wherein R6 and R7 may be the same or different and are respectively hydrogen, C1-4 alkyl or aralkyl or may form together with the nitrogen atom a 5- or 6-membered heterocyclic group which may further contain a nitrogen, oxygen or sulfur atom); and m and n each are zero or a positive integer and m + n is no more than 11.