BENZENE-SULFONYL UREAS AND PROCESS FOR PREPARING THEM

摘要

Cpds of formula (I): (where R is lower alkyl, lower alkoxy, halogen, NH2, CF3, MeCO or acylaminoalkyl (acyl is the residue of a (cyclo) aliphatic, aromatic or heterocyclic carboxylic acid or of a carbamic acid, and alkyl is 1-4C); R1 is lower alkyl, cycloalkyl or cycloalkylalkyl (all opt. substd by lower alkoxy) or a polycyclic residue opt. bonded to N via lower alkyl; R2 is H or NR1R2 is a 5- to 7-membered ring opt. substd by lower alkyl of endoalkylene), and their salts are prepd by cleaving a cpd of formula (II): (where R3 is 1-3C alkyl) with a pri. or sec. amine.