| 摘要 |
The present invention relates to compounds of the formula: <IMAGE> wherein A represents a grouping of the formula: <IMAGE> <IMAGE> B represents a single bond or a straight- or branched-chain alkylene group containing from 1 to 9 carbon atoms, W represents ethylene or trans-vinylene, X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R represents a hydroxymethyl group or a grouping of the formula -COOR4, in which R4 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R1 represents a hydrogen atom or a methyl or ethyl group, R2 represents a hydrogen atom or a methyl or ethyl group and R3 represents a hydrogen or chlorine atom or a hydroxy group and cyclodextrin clathrates of such alcohols, acids and esters and, when R4 in the formula -COOR4 represents a hydrogen atom, non-toxic salts thereof, and intermediates therefor. These compounds exhibit characteristic prostaglandin-like activity.
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