摘要 |
Antimicrobial compositions comprising as active ingredient at least one compound of the general formula <IMAGE> I (wherein R1 and R5, which may be the same or different each represent a hydrogen or halogen atom and R2, R3 and R4 which may be the same or different, each represent a hydrogen atom or a lower alkyl group) in association with an antimicrobial carrier, excipient or diluent. The compounds of formula I may be prepared by reacting a corresponding dihydrothiazolo 8-oxide compound with a base. Certain of the compounds of formula I are novel and may also be prepared by pyrolytic decarboxylation of a corresponding carboxyl substituted thiazolo-8-oxide compound. |