| 摘要 |
The present invention relates to compounds of the formula: <IMAGE> VII wherein A represents a grouping of the formula: <IMAGE> VIIIA <IMAGE> VIIIB <IMAGE> IV B represents an oxygen or sulphur atom, R1 and R2, which may be the same or different, each represent a hydrogen or halogen atom, a trifluoromethyl group, or a straight- or branched-chain alkyl or alkoxy group containing from 1 to 4 carbon atoms, R represents a group of the formula -COOR3, in which R3 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, or a group of the formula -CH2OR4, in which R4 represents a hydrogen atom or an alkylcarbonyl group containing from 2 to 5 carbon atoms and the double bonds depicted in positions C2-C3, C5-C6 and C13-C14 are trans, cis and trans respectively, the cyclodextrin clathrates thereof and, when R3 in the group -COOR3 represents a hydrogen atom, non-toxic salts thereof. These compounds exhibit characteristics of prostaglandin-like activity.
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