| 摘要 |
<p>1495640 Tetrahydroquinolines BEECHAM GROUP Ltd 23 July 1976 [28 July 1975] 31426/75 Heading C2C Compounds of the general formula (R=H, Me, Et; R 1 =Ph optionally substituted by F, Cl, Br, CF 3 , Me or OMe, naphthyl; R 2 = H, Me; R 3 =H, Me, Et, PhCH 2 ; X = CHR 5 CHR 4 , CHR 5 CH 2 CHR 4 ; R 4 , 5 = H, Me) and their salts are prepared by standard methods, e.g. by the following routes illustrating the case in which XNR 2 R 3 = (CH 2 ) 2 NMe 2 and R = H, Me optionally followed by salt formation. The above compounds are antidepressants and anorectics, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.</p> |
