发明名称 7-Acylamino-3-{8 1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl{9 -3-cephem-4-carboxylic acids
摘要 New semisynthetic cephalosporins characterized by having structures with a 1-dihydroxypropyltetrazole-5-ylthiomethyl group at position 3. Exemplary is the antibacterially effective 7-D-mandelamido-3-[1-(2,3-dihyroxypropyl)tetrazole-5-ylthiomethyl]-3-c ephem-4-carboxylic and 7-(D- alpha -phenyl- alpha -aminoacetamido)-3-[1-(2,3-dihydroxypropyl)-tetrazole-5-ylthiomethyl]- 3-cephem-4-carboxylic acid.
申请公布号 US4064242(A) 申请公布日期 1977.12.20
申请号 US19760738774 申请日期 1976.11.04
申请人 SMITHKLINE CORPORATION 发明人 SCHMIDT, STANLEY J.
分类号 A61K31/345;A61K31/545;A61K31/546;A61P31/04;C07D501/36;(IPC1-7):A61K31/34 主分类号 A61K31/345
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