摘要 |
New semisynthetic cephalosporins characterized by having structures with a 1-dihydroxypropyltetrazole-5-ylthiomethyl group at position 3. Exemplary is the antibacterially effective 7-D-mandelamido-3-[1-(2,3-dihyroxypropyl)tetrazole-5-ylthiomethyl]-3-c ephem-4-carboxylic and 7-(D- alpha -phenyl- alpha -aminoacetamido)-3-[1-(2,3-dihydroxypropyl)-tetrazole-5-ylthiomethyl]- 3-cephem-4-carboxylic acid.
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