STOFFZUSAMMENSETZUNGEN AUF BASIS VON ISOCYANAT-REAKTRIONSPRODUKTEN, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG

摘要

Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with compounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives receptive to tagging, as by radiolabeling. The tagged derivatives may then be employed to determine the presence of the compound of interest in nanomolar or even picomolar amounts by using clinical analysis techniques such as radioimmunoassay.