Acetylthio amides and esters were prepared by the free radical addition of thiolacetic acid to the terminal and nonterminal double bonds of N-substituted fatty amides and fatty esters. The free radical additions of the thiolacetic acid to the unsaturated compounds were initiated by irradiation using cobalt-60. The process using irradiation with cobalt-60 was also used to bring about the addition of bromotrichloromethane to N-substituted fatty amides and fatty esters to produce halogen-containing amides and esters. These new sulfur or halogen-containing compounds were found to have antimicrobial activity and to possess properties making them useful as antimicrobial agents.
申请公布号
US4062841(A)
申请公布日期
1977.12.13
申请号
US19760744583
申请日期
1976.11.23
申请人
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
发明人
MOD, ROBERT R.;HARRIS, JAMES A.;ARTHUR, JR., JETT C.;MAGNE, FRANK C.;SUMRELL, GENE;NOVAK, ARTHUR F.